Creatine is a popular supplement used by athletes and bodybuilders to enhance their performance and muscle mass. However, some people have raised concerns about its potential effects on kidney health, including the risk of developing kidney stones. This article will examine the evidence that can creatine cause kidney stones, as well as provide recommendations and precautions for those considering taking creatine supplements.
The Connection between Creatine and Kidney Stones
What are Kidney Stones?
Kidney stones are solid formations of mineral and acid salts that form in the kidneys and can cause severe pain when passing through the urinary tract.
They can be made up of various substances, including calcium oxalate and calcium phosphate, which are commonly found in the urine of individuals with kidney stones.

How can Creatine cause Kidney Stones?
Creatine is a nitrogenous organic acid that is found in the muscles and is commonly used as a supplement to enhance athletic performance.
When taken in large doses, it may increase the amount of creatinine in the blood, leading to a high concentration of substances such as calcium and oxalate in the urine. These substances can increase the risk of forming kidney stones.
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Research on the subject
Studies on the link between creatine and kidney stones have produced mixed results, with some suggesting a potential risk while others have found no significant connection.
A review of 11 studies on the subject found that creatine supplementation may increase the risk of developing kidney stones in certain populations, but further research is needed to fully understand the connection.
Individuals with pre-existing kidney problems or those taking certain medications may be at a higher risk of developing kidney stones when taking creatine supplements. It is also crucial to drink plenty of water when taking creatine to help prevent the formation of kidney stones.
the evidence on the connection between creatine and kidney stones is still limited, it is recommended to be cautious and to consult with a healthcare provider before starting a creatine supplement regimen.
Further research is needed to fully understand the potential risks and benefits of creatine supplementation.
Precautions and Recommendations
Dosage of Creatine
The recommended dose of creatine varies based on factors such as age, weight, and athletic performance goals.
It is crucial to follow the recommended dosage on the label and to not exceed the recommended amount.
Taking excessive amounts of creatine can increase the concentration of creatinine in the blood and potentially lead to an increased risk of kidney stones.

Monitoring of Kidney Function
It is important for individuals taking creatine supplements to regularly monitor their kidney function, especially if they have pre-existing kidney problems.
This can be done through routine blood tests to check creatinine levels and kidney function. If kidney function decreases or if creatinine levels become elevated, it is recommended to discontinue the use of creatine and seek medical attention.

Alternative Supplements
If individuals are concerned about the potential risks of creatine supplementation, they may consider alternative supplements that have a lower risk of affecting kidney health.
For example, beta-alanine and citrulline are commonly used as pre-workout supplements and do not appear to have a significant impact on kidney function.
Be cautious when taking creatine supplements and to follow recommended dosages. Regular monitoring of kidney function and seeking medical advice is also crucial, especially for individuals with pre-existing kidney problems.
If in doubt, it is recommended to consider alternative supplements or to seek advice from a healthcare provider.
Conclusion
The link between creatine and kidney stones is a topic of ongoing research, with some studies suggesting a potential risk and others finding no significant connection.
However, it is important to be cautious when taking creatine supplements and to follow recommended dosages. Regular monitoring of kidney function and seeking medical advice is also crucial, especially for individuals with pre-existing kidney problems.
While the potential risks of creatine supplementation are still not fully understood, it is important to be informed and to make informed decisions when considering using this supplement. This includes consulting with a healthcare provider and regularly monitoring kidney function.
It is crucial to seek the advice of a healthcare provider before starting a creatine supplement regimen, especially for individuals with pre-existing kidney problems or those taking certain medications. A healthcare provider can provide personalized recommendations and help determine the best course of action based on individual health and wellness goals.
References
- Kidney Stones. National Kidney Foundation. (2021). https://www.kidney.org/atoz/content/kidney-stones
- Creatine Monohydrate. Examine.com. (2021). https://examine.com/supplements/creatine-monohydrate/
- Creatine Supplementation and Kidney Function. Sports Medicine. (2017). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768647/
- The Safety of Creatine Supplementation: A Systematic Review. Nutrition Reviews. (2015). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747335/
- The Effect of Creatine Supplementation on Kidney Function. Sports Medicine. (2018). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824082/
These references provide additional information on the subject of kidney stones and creatine supplementation, including potential risks and benefits, as well as recommended precautions and monitoring strategies.
It is important to consult with a healthcare provider for personalized recommendations and to seek further medical advice as needed.
FAQS
Q: Can creatine cause kidney stones?
A: There is some evidence to suggest a potential link between creatine supplementation and the development of kidney stones, although the evidence is not conclusive. It is important to be cautious and to follow recommended dosages, as well as regularly monitoring kidney function, especially for individuals with pre-existing kidney problems.
Q: Is creatine safe for people with kidney problems?
A: It is not recommended for individuals with pre-existing kidney problems to take creatine supplements without medical supervision. It is important to consult with a healthcare provider and to regularly monitor kidney function while taking creatine.
Q: What is the recommended dosage of creatine?
A: The recommended dosage of creatine varies based on factors such as age, weight, and athletic performance goals. It is important to follow the recommended dosage on the label and not to exceed the recommended amount, as taking excessive amounts of creatine can increase the risk of kidney stones and affect kidney function.
Q: Are there alternative supplements to creatine that do not affect kidney function?
A: Yes, alternative supplements such as beta-alanine and citrulline are commonly used as pre-workout supplements and do not appear to have a significant impact on kidney function. It is important to consult with a healthcare provider to determine the best supplement regimen based on individual health and wellness goals.